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Musikhina Natalya Alekseevna

Head, Department of Emergency Cardiology of the Scientific Division of Clinical Cardiology


MD, PhD, Head, Department of Emergency Cardiology of the Scientific Division of Clinical Cardiology, Tyumen Cardiology Research Center

Contact details
e-mail:
Tel.: +7 (3452) 68-77-19 ext. 1389
Fax: +7 (3452) 20-76-41

Brief biography
In 1976 Natalya Musikhina graduated from Tyumen State Medical University. In 1983-1986, after her internship, she worked as a therapist of Chugunaevo hospital in the Tyumen region. Upon completion of clinical residency in the internal diseases, she has been employed at Tyumen Cardiology Research Center since 1988 as a cardiologist and junior scientific researcher, and then she became the Head of the Department of Arterial Hypertension and senior scientific researcher. Since 2009, she was appointed as the Head of the Department of Emergency Cardiology of the Scientific Division of Clinical Cardiology. In 1996, Dr. Musikhina successfully defended her PhD thesis in cardiology; in 1997, she received the highest category as a doctor.

Research interests
Natalya Musikhina is an author of over 100 research papers, 1 book; a co-author of 3 patents on the inventions and one computer program.
The main scientific researches of N.A. Musikhina are connected with studying of pathogenic aspects of correlation of coronary artery disease and arterial hypertension, issues of vascular wall inflammatory response in patients with arterial hypertension and various forms of coronary artery disease. Besides, she is a coordinator of several international clinical studies devoted to prevention of vascular damages in patients with acute coronary syndrome with and without ST segment elevation performed at the Department of Emergency Cardiology.

Achievements, awards, and grants
N.A. Musikhina is awarded with Certificate of Merit from the Ministry of Health Care and Social Development in 2010, a Letter of Gratitude from the Governor of the Tyumen region for the significant contribution to healthcare of the Tyumen region in 2009. Her scientific project “Variability of heart rhythm and endothelium function in patients with coronary artery disease, ivabradine impact” got support from the Governor of the Tyumen region at the grants competition due to the importance of this issue for the region. Dr. Musikhina is a member of National Scientific Society on Inflammation and European Atherosclerosis Society.

Main publications
1. FREE-RADICAL LIPID OXIDATION IN EXPERIMENT AND CLINIC /Uhkalova V.N., Ioanidis N.V., Kadochnikova G.D., Deeva Z.M., Tikhonova V.V., Perevozkina M.G., Moskvichev Y.A., Gapon L.I., Galyan S.L., Shafer M.Z., Kirshenbaum I.R., Musikhina N.A., Petelina T.I., Gultyaeva E.P., Baryshnikov A.V. - Tyumen: Tyumen State University publishing, 1997. - 132 p.

2. CALCULATOR OF THE RISK ESTIMATION OF EXCEEDING DIAGNOSTIC INDICATOR: VELOCITY OF PULSE WAVE DISTRIBUTION «ARTERIAL STIFFNESS» / Petelina T.I., Gapon L.I., Avdeeva K.S., Dyachkov S.M., Musikhina N.A., Kuznetsov V.A. // Certificate No. 2016614527 on the state registration of the computer program from 26.04.2016.

3. THE METHOD OF DIAGNOSTICS OF THE RIGIDITY OF THE VASCULAR WALL INDICATOR IN PATIENTS WITH ARTERIAL HYPERTENSION AND ABDOMINAL OBESITY / Petelina T.I., Gapon L.I., Avdeeva K.S., Musikhina N.A., Dyachkov S.M. // Patent for invention No. 2567606 dated November 05, 2014.

4. THE METHOD OF DIAGNOSTICS OF HYPERTENSIVE DISEASE / Vershinina A.M., Gapon L.I., Doroshenko A.A., Shurkevich N.P., Musikhina N.A., Bazhukhina I.F. // Patent for invention No. 2203494 dated April 27, 2003.

5. THE METHOD OF DIAGNOSTICS OF CORONARY ARTERY DISEASE IN PATIENTS WITH ARTERIAL HYPERTENSION / Shafer M.Zh., Kuznetsov V.A., Musikhina N.A., Gultyayeva E.P., Gapon L.I. // Patent for invention No. 2145087 dated 27.01.2000.

6. FEATURES OF BIOCHEMICAL PARAMETERS OF BLOOD SERUM IN PATIENTS WITH STABLE ANGINA AND TYPE 2 DIABETES MELLITUS / Petelina T.I., Musikhina N.A., Gapon L.I., Sharoyan Y.A., Gorbatenko E.A. // Endocrinology & Metabolism International Journal - 2018. –Vol. 6, Issue 1 00147. DOI: 10/15406/emij.2018/06/00147.

7. PROSPECTIVE ANALYSIS OF LIPID PROFILE PARAMETERS AND MARKERS OF VASCULAR INFLAMMATORY RESPONSE WITH PROGNOSIS OF UNDESIRABLE CORONARY EVENTS IN PATIENTS WITH CORONARY HEART DISEASE AFTER ANGIOPLASTY WITH STENTING / Petelina TI, Musikhina NA, Gapon LI, Gorbatenko EA, Dyachkov SM, Sharoyan YA, Zueva EV // Klin Lab Diagn. 2018; 63(8):471-477. doi: 10.18821/0869-2084-2018-63-8-471-477. PMID: 30726650.

8. BIOCHEMICAL PARAMETERS OF LIPID METABOLISM IN PATIENTS WITH UNSTABLE ANGINA AND HEMODYNAMICALLY SIGNIFICANT CORONARY STENOSIS / Petelina T., Musikhina N., Gapon L., Takkand A., Osipova I., Belosludtseva O. // Vrach (The Doctor).- 2015.- № 4.- p. 71-74.

9. CEREBRAL BLOOD FLOW AND ENDOTHELIAL FUNCTIONAL ACTIVITY IN PATIENTS WITH CORONARY HEART DISEASE AND ARTERIAL HYPERTENSION DURING THERAPY WITH IVABRADINE IN COMBINATION WITH PERINDOPRIL / Musikhina NA, Gapon LI, Utesheva AB, Petelina TI, Kolesnikova SN. // Ter Arkh. 2012; 84(12):30-4. PMID: 23479985.

10. IMPACT OF IVABRADINE IN COMPLEX THERAPY WITH PERINDOPRIL ON HEART RHYTHM VARIABILITY IN PATIENTS WITH CORONARY ARTERY DISEASE AND ARTERIAL HYPERTENSION / Musikhina N.A., Gapon L.I., Utesheva A.B., Petelina T.I. // Heart: journal for clinical physicians.-2011.-V.10, №3(59).- p.137 - 139. http://elibrary.ru/item.asp?id=17782895.

11. STRUCTURAL-FUNCTIONAL PROPERTIES OF THE VASCULAR WALL IN HYPERTENSIVE PATIENTS WITH CORONARY HEART DISEASE: EFFECTS OF FELODIPIN AND PERINDOPRIL / Musikhina NA, Yuferova OV, Gapon LI, Makhneva EA, Belikova EA, Petelina TI, Todosiychuk VV. // Ter Arkh. 2009; 81(9):13-6. PMID: 19827645.

12. LIPID PROFILE AND BIOCHEMICAL MARKERS OF INFLAMMATION IN PATIENTS WITH UNSTABLE ANGINA AND OBSTRUCTIVE VERSUS NON-OBSTRUCTIVE CORONARY ARTERY DISEASE / N. Musikhina, T. Petelina, N. Galeeva, A. Kostousova, L. Gapon. // Atherosclerosis, Vol 275, e114, P1.1.036. Abstracts of the 86th European Atherosclerosis Society (EAS) Congress – 2018, May 05-08, Lisbon, Portugal. DOI: https://doi.ore/10.1016/ i.atherosclerosis.2018.06.321.

13. THE ROLE OF STATINS IN PREVENTION OF ACUTE CORONARY EVENTS IN PATIENTS WITH CORONARY HEART DISEASE BEFORE AND AFTER CORONARY ANGIOPLASTY AND STENTING / T. Petelina, N. Musikhina, L. Gapon, U. Sharoyan. // Atherosclerosis, Vol 275, e223, P5.2.414. Abstracts of the 86th European Atherosclerosis Society (EAS) Congress – 2018, May 05-08, Lisbon, Portugal. DOI: https://doi.ore/10.1016/i.atherosclerosis.2018.06.701.

14. RELATIONSHIP OF ENDOTHELIAL FUNCTION AND CIRCADIAN INDEX OF BLOOD PRESSURE IN PATIENTS WITH ARTERIAL HYPERTENSION AND CORONARY ARTERY DISEASE / Musikhina N.A., Petelina T.I., Roshal O.V., Gapon L.I., Zyrianova L.I. // Journal of Hypertension: Abstracts of the 28 European Meeting on Hypertension and Cardiovascular Protection, Barcelona, Spain, 8-11 June, 2018- Volume 36,e-Supplement 1, e204.

15. INFLAMMATORY MARKERS IN PATIENTS WITH ACUTE CORONARY SYNDROME / NA Musikhina, TI Petelina, AI Kostousova, UA Sharoyan // European Heart Journal - Acute Cardiovascular Care 2018: Volume: 7 issue: 1_suppl, page: 262. Article first published online: March 2, 2018; Issue published: March 1, 2018 https://doi.org/10.1177/2048872617751067.

16. VASCULAR WALL STIFFNESS PARAMETERS AS RISK FACTORS OF CEREBROVASCULAR COMPLICATIONS IN HYPERTENSIVE PATIENTS WITH ABDOMINAL OBESITY / Avdeeva К.S., Petelina T.I., Gapon L.I., Musikhina N.A., Kopylova L.N. // Cardiovascular Research: Frontiers in Cardiovascular Biology 2018, April 20-22, Vienna, Austria 114 (suppl_1): P 115.

17. INFLAMMATORY MARKERS IN PATIENTS WITH UNSTABLE ANGINA AFTER CORONARY ANGIOPLASTY AND STENTING/ Musikhina N.A., Petelina T.I., Gapon L.I., Kuznetsov V.A.// Global heart: Abstract of the World Congress of Cardiology & Cardiovascular Health (WCC) 2016, from 4 to 7 June 2016, Mexico City, Mexico.- Vol. 11, Issue 2, Supplement.- e94 PM134.

18. PROGNOSTIC SIGNIFICANCE OF ATHEROGENIC LIPID PROFILE AND INFLAMMATORY MARKERS IN PATIENTS WITH CORONARY ARTERY DISEASE AND DIABETES RECEIVING STANDARD MEDICAL THERAPY: A FOLLOW-UP STUDY/ Petelina T.I., Musikhina N.A., Gapon L.I., Kuznetsov V.A.// Global heart: Abstract of the World Congress of Cardiology & Cardiovascular Health (WCC) 2016, from 4 to 7 June 2016, Mexico City, Mexico.- Vol. 11, Issue 2, Supplement.- e178 PM 311.

19. CHARACTERISTICS OF THE INFLAMMATORY RESPONSE IN PATIENTS WITH CORONARY ARTERY DISEASE AND ARTERIAL HYPERTENSION/ N.A. Musikhina, T.I. Petelina, L.I. Gapon, E.A.. Gorbatenko, Yu.V. Potolinskaya, E.V. Arkhipova// Cardiovascular Research: Abstract of the Frontiers in cardiovascular biology, 8 - 10 July, 2016, Florence Italy.-Volume 111, Issue suppl 1, 1 July 2016.- S97.

20. ASSOCIATION BETWEEN BIOCHEMICAL MARKERS OF LIPID PROFILE AND INFLAMMATORY REACTION AND STIFFNESS OF THE VASCULAR WALL IN HYPERTENSIVE PATIENTS WITH ABDOMINAL OBESITY / TI. Petelina, LI. Gapon, NA. Musikhina, KS. Avdeeva, SM. Dyachkov// Cardiovascular Research: Abstract of the Frontiers in cardiovascular biology, 8 - 10 July, 2016, Florence Italy.-Volume 111, Issue suppl 1, 1 July 2016.- S74.

21. IDENTIFYING FEATURES OF VASCULAR INFLAMMATORY RESPONSE IN PATIENTS WITH MYOCARDIAL INFARCTION USING THE SYNTAX SCORE/T. Petelina, N. Musikhina, L. Gapon, I. Osipova, V. Kuznetsov//Atherosclerosis: Abstracts of the 84th European Atherosclerosis Society Annual Congress, May 29-June 01, 2016, Innsbruck, Austria.- Volume 252, September 2016.- e180.