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Tatiana I. Petelina

Tatiana I. Petelina

Petelina Tatiana Ivanovna MD, PhD, Deputy Director for Research, Professor of Educational Methodical Department, Cardiologist of the highest category Head of the Laboratory of Clinical & Diagnostic and Molecular & Genetic Studies, Leading Scientific Researcher of the Department of Arterial Hypertension and Coronary Insufficiency, Tyumen Cardiology Research Center – Branch of Tomsk National Research Medical Center

Contact information

e-mail: Petelina@infarkta.net

Tel.: +7 (3452) 68-14-14 (ext.12-36)

Fax: +7 (3452) 28-09-94 

Brief biography

In 1983 Dr. Petelina graduated from General Medicine Faculty of Tyumen State Medical University. After internship, she worked as a therapist of the Outpatient Department since 1984, then completed the residency in cardiology and since 1989 worked as cardiologist, Junior Scientific Researcher (1993), Scientific Researcher (1994), Senior Scientific Researcher(2000), Leading Scientific Researcher (since 2017 to present) of the Department of Arterial Hypertension and Coronary Insufficiency, since 2018 she has held the position of Deputy Director for Research of Tyumen Cardiology Research Center – Branch of Tomsk National Research Medical Center. Dr. Petelina successfully defended her PhD thesis in cardiology in 2005.

Research interests

Petelina Tatiana Ivanovna is an author of over 200 research papers, an owner of 4 patents on invention, 1 databases, 1 software program, which received state registration. Her scientific interest is studying of fundamental aspects of arterial hypertension pathogenesis, metabolic syndrome and coronary artery disease using immunoenzyme and molecular genetic research methods, development and implementation of new algorithms and methods of personalized diagnostics and treatment at stages of the cardiovascular continuum.

Achievements, awards, and grants

Petelina T.I. was awarded a Certificate of Merit and Letter of appreciation of Healthcare Department of Tyumen region for many years of conscientious and impeccable work in the field of medical science and health care, for a significant contribution to the socio-economic development of the Tyumen Region (2005, 2011), Certificate of Honor from the Tyumen region Duma (2006), Certificate of Merit from the Department of Education and Science of the Tyumen region (2007), Certificate of Honor from the Tyumen Administration (2009), Certificate of Merit of Russian Academy of Sciences (2017). In 2019, she was awarded the Honorary Title "Honored Veteran of the Siberian Branch of the Russian Academy of Sciences".

Main Publications

1.       Patent of the Russian Federation for the invention “METHOD FOR PREDICTING ISCHEMIC CARDIAC DISEASE IN PATIENTS WITH ARTERIAL HYPERTENSION” No. 2316995, Int. Cl. A61B5/02 (2006.01), Vetoshkin Aleksandr Semenovich, Shurkevich Nina Petrovna, Petelina Tat'jana Ivanovna, Gapon Ljudmila Ivanovna, Bakhmatova Julija Aleksandrovna, Gorbatenko Elena Aleksandrovna; proprietor: Tomsk National Research Medical Center of the Russian Academy of Sciences. Application: 2006120142/14, 2006.06.08; date of publication: 2008.02.20 Bull. № 5.

2.       Patent of the Russian Federation for the invention “METHOD FOR EVALUATING CLINICAL THERAPEUTIC EFFICIENCY IN PATIENTS WITH ARTERIAL HYPERTENSION“ No. 2316996, Int. Cl. A61B 5/02(2006.01), Petelina Tat'jana Ivanovna, Gapon Ljudmila Ivanovna, Kalinina Veronika Andreevna proprietor: Tomsk National Research Medical Center of the Russian Academy of Sciences.Application: 2006120143/14, 2006.06.08; date of publication: 2008.02.20 Bull. № 5.

3.       Patent of the Russian Federation for the invention “METHOD FOR DETERMINING DIAGNOSTIC CRITERION OF VASCULAR WALL STIFFNESS IN PATIENTS SUFFERING ARTERIAL HYPERTENSION ACCOMPANIED BY ABDOMINAL OBESITY “ No. 2567606, Int. Cl. A61B 5/02(2006.01), G01N 33/49(2006.01), Petelina Tat'jana Ivanovna, Gapon Ljudmila Ivanovna, Avdeeva Ksenija Sergeevna, Musikhina Natal'ja Alekseevna, D'jachkov Sergej Mikhajlovich; proprietor: Tomsk National Research Medical Center of the Russian Academy of Sciences. Application: 2014144758/14, 2014.11.05; date of publication: 2015.11.10 Bull. № 31.

4.      Patent of the Russian Federation for the invention “METHOD FOR PREDICTATION OF SUPER RESPONSE TO CARDIAC RESYNCHRONIZATION THERAPY FOR PATIENTS WITH CHRONIC HEART FAILURE “ No. 2623487, Int. Cl. A61B 5/00(2006.01), A61B 8/06(2006.01), G01N 33/49(2006.01), Kuznetsov Vadim Anatolevich, Soldatova Anna Mikhajlovna, Krinochkin Dmitrij Vladislavovich, Enina Tatyana Nikolaevna, Petelina Tatyana Ivanovna, Rychkov Aleksandr Yurevich Melnikov Nikolaj Nikolaevich; proprietor: Tomsk National Research Medical Center of the Russian Academy of Sciences. Application: 2016111758, 2016.03.29; date of publication: 2017.06.26 Bull. № 18.

5.      Certificate on state registration of the database " Database on assessing the relationship of biochemical parameters of the inflammatory reaction and the elastic properties of the vascular wall in patients with arterial hypertension " No. 2017621477 / Etelina Tatyana Ivanovna (RU), Avdeeva Ksenia Sergeevna (RU), Gapon Lyudmila Ivanovna (RU), Musikhina Natalya Alekseevna (RU), Sergeychik Oksana Ivanovna (RU); Date of state registration in the Database Register December 13, 2017.

6.      Certificate on state registration of the database " CALCULATOR OF THE RISK ESTIMATION OF EXCEEDING DIAGNOSTIC INDICATOR: VELOCITY OF PULSE WAVE DISTRIBUTION «ARTERIAL STIFFNESS»" No. 2016614527 / Petelina T.I., Gapon L.I., Avdeeva K.S., Dyachkov S.M., Musikhina N.A., Kuznetsov V.A.; Applicant and proprietor: Tomsk National Research Medical Center of the Russian Academy of Sciences. Application: 2016611670; registration: 26.04.2016

7.      Petelina T.I., Musikhina N.A., Gapon L.I., Dyachkov S.M., Sharoyan Y.A. Рrospective analysis of lipid spectrum parameters and vascular inflammatory markers as a variant of a personified approach to prognosis of undesirable coronary events in patients with coronary heart disease after angioplasty // Periodico Tche Quimica. – 2019. – V.16, №33. P.277-288.

8.      Petelina T.I., Musikhina N.A., Gapon L.I., SharoyanY.A., Gorbatenko E.A. Features of Biochemical Parameters of Blood Serum in Patients with Stable Angina and Tyre 2 Diabetes Mellitus// Endocrinology & Metabolism International Journal - 2018. –Vol. 6, Issue 1 00147. DOI: 10/15406/emij.2018/06/00147

9.      Gender in cardiac resynchronisation therapy/Tatiana N. Enina, Vadim A. Kuznetsov, Anna M. Soldatova, Tatiana I. Petelina, Dmitriy V. Krinochkin, Alexander Yu. Rychkov, Olga Yu. Nochrina// Journal of Cardiovascular and Thoracic Research. - 2018, 10(4), 197-202 DOI: 10.15171/jcvtr.2018.34

10. Tatiana I Petelina, Natalia A Musikhina, Liudmila I Gapon, Vadim A Kuznetsov, Elena A Gorbatenko, Irina V Emenеva. Specific parameters of lipid spectrum and markers of vascular inflammation in patients with stable angina and significant coronary artery stenosis with or without diabetes mellitus type 2. A prospective follow-up after angioplasty// Integrative Obesity and Diabetes, 2017. Volume 3(2): 1-8   DOI: 10.15761/IOD.1000175 ISSN: 2056–8827)

11. Petelina T.I., Musikhina N.A., Gapon L.I., Emeneva I.V., Gorbatenko E.A. Lipid profile and markers of vascular inflammation in patients with stable angina in the presence and absence of type 2 diabetes mellitus//Diabetes mellitus.– 2017.- Vol.20– №30. – P. 194–200

12. Alexander A. Zakharov, Evgeni A. Olennikov, Tatyana I. Payusova, Tatyana I. Petelina, Natalia A. Musikhina, Ludmila I. Gapon. Scientific data analysis using neural networks as exemplified in defining the factors impacting the C-reactive protein level// Biology and Medicine. – 2016.- Vol. 8, Issue 6 DOI: 10.4172/0974-8369.1000329

13. Petelina Tatiana Ivanovna1, Avdeeva K.S.1, Bykova S.G.1, Musikhina N.A.1, Gapon L.I.1, Gorbatenko E.A.1, Zueva E.V.1, Leonovich S.V.1, Lystsova N.L. NON-SPECIFIC PARAMETERS OF IMMUNE RESPONSE AS A RING IN THE PATHOGENESIS OF REMODELING OF THE VASCULAR WALL AND DESTRUCTION OF BONE TISSUE IN WOMEN WITH ARTERIAL HYPERTENSION IN POSTMENAPUS // Russian Clinical Laboratory Diagnostics Journal. - 2019. - V.64, No 7. - P.417-423. DOI: https://doi.org/10.18821/0869-2084-2019-64-7-417-423

14. Petelina T.I., Musikhina N.A., Gapon L.I., Gorbatenko E.A., Emeneva I.V., Sharoyan Yu.A., Zueva E.V. PROSPECTIVE ASSESSMENT OF VASCULAR INFLAMMATORY RESPONSE MARKERS AND LIPID PROFILE PARAMETERS IN PATIENTS WITH CORONARY ARTERY DISEASE IN THE PRESENCE AND ABSENCE OF TYPE 2 DIABETES MELLITUS WHO UNDERWENT ANGIOPLASTY WITH STENTING OF THE CORONARY ARTERIES // Cytokines and inflammation. - 2019.- V.18, No. 1. - P. 27-35.

15. Enina Tatiana, Kuznetsov Vadim, Soldatova Anna, Petelina Tatiana, Dyachkov Sergey, Krinochkin Dmitriy SEX HORMONES LEVEL AND EFFECT OF CARDIAC RESYNCHRONIZATION THERAPY IN MEN // Kardiologiia Journal. - 2018.- V 58, No. 7S.- P. 24- 35 DOI: 10.18087/cardio.2464

16. Musikhina N.A., Petelina T.I., Emeneva I.V., Dyachkov S.M. BIOCHEMICAL MARKERS OF INFLAMMATION IN PATIENTS WITH ACUTE CORONARY SYNDROME // Atherosclerosis. - 2019. - V.15, No. 3. P.56-61 DOI: https://doi.org/10.15372/ATER20190305

17. Petelina T.I., Musikhina N.A., Gapon L.I., Dyachkov S.M., Sharoyan Y.A. РROSPECTIVE ANALYSIS OF LIPID SPECTRUM PARAMETERS AND VASCULAR INFLAMMATORY MARKERS AS A VARIANT OF A PERSONIFIED APPROACH TO PROGNOSIS OF UNDESIRABLE CORONARY EVENTS IN PATIENTS WITH CORONARY HEART DISEASE AFTER ANGIOPLASTY// Russian Clinical Laboratory Diagnostics Journal. Vol. 63.8.2018. P.471-477.DOI: http://dx.doi.org/10.18821/0869-2084-2018-63-8-471-477

18. Musikhina Natal'ya Alekseevna, Petelina Tat'yana Ivanovna, Bessonov Ivan Sergeevich, Galeeva Natal'ya Alimgiraevna, Gorbatenko Elena Aleksandrovna, Kostousova Alina Igorevna. COMPARATIVE ANALYSIS OF THE INFLAMMATORY RESPOND OF THE VASCULAR WALL AFTER IMPLANTATION OF BIORESORBABLE SCAFFOLDS AND EVEROLIMUS COVERED STENTS IN PATIENTS WITH STABLE CORONARY ARTERY DISEASE // Siberian Scientific Medical Journal. - 2018.-V. 38, No. 4.-P.73-79. DOI: 10.15372 / SSMJ20180409

19. Petelina Tatiana I., Musikhina Natalia A., Gapom Liudmila I., Емеneva Irina V., Gorbatenko Elena A. LIPID PROFILE AND MARKERS OF VASCULAR INFLAMMATION IN PATIENTS WITH STABLE ANGINA IN THE PRESENCE AND ABSENCE OF TYPE 2 DIABETES MELLITUS // Diabetes Mellitus. - 2017.- V. 20, No. 3.- P. 194-200

20. Musikhina Natalia A., Gapon Ludmila I., Petelina Tatiana I., Makhneva Elena A., Emeneva Irina V. ENDOTHELIAL DYSFUNCTION AND HEART RATE VARIABILITY IN PATIENTS WITH ARTERIAL HYPERTENSION AND CORONARY ARTERY DISEASE// Arterial hypertension.- 2016.- No. 4.- P. 414-424.

21. Petelina T., Avdeeva K., Gapon L., Musikhina N., Gorbatenko E. ELASTIC PROPERTIES OF THE VASCULAR WALL AND THEIR RELATIONSHIP TO SERUM BIOCHEMICAL MARKERS IN HYPERTENSIVE PATIENTS WITH ABDOMINAL OBESITY// The Doctor journal -2015.- No 5.- P. 71-74

22. Petelina T., Musikhina N., Gapon L., Takkand A., Osipova I., Belosludtseva O. BIOCHEMICAL PARAMETERS OF LIPID METABOLISM IN PATIENTS WITH UNSTABLE ANGINA AND HEMODYNAMICALLY SIGNIFICANT CORONARY STENOSIS// The Doctor journal.- 2015.- No 4.-P. 71-74

23. Petelina T.I., N.A. Musikhina, L.I. Gapon, N.V. Dementieva, V.A. Kuznetsov, N.L. Lystsova PROGNOSTIC SIGNIFICANCE OF LABORATORY PARAMETERS OF BLOOD SERUM IN PATIENTS WITH CORONARY ARTERY DISEASE IN COMBINATION WITH DIABETES MELLITUS AGAINST THE BACKGROUND OF STANDARD THERAPY: A FOLLOW-UP STUDY// Russian Heart Journal. - 2013.- No. 6. - P. 371-377

24. Petelina T.I., Musikhina N.A., Gapon L.I., Dement'eva N.V., Lystsova N.L., Takkand A.G., Petrashevskaia T.G., Zyrianov I.P. BLOOD CHEMISTRY ANALYSIS IN PATIENTS WITH CORONARY ARTERY DISEASE: PROSPECTIVE OBSERVATION AFTER TRANSLUMINAL BALLOON ANGIOPLASTY// Russian Journal of Cardiology and Cardiovascular Surgery.- 2013.- V.6, No.5.- P. 17-21

25. Musikhina N.A., Gapon L.I., Utesheva A.B., Petelina T.I., Kolesnikova S.N. CEREBRAL BLOOD FLOW AND ENDOTHELIAL FUNCTIONAL ACTIVITY IN PATIENTS WITH CORONARY HEART DISEASE AND ARTERIAL HYPERTENSION DURING THERAPY WITH IVABRADINE IN COMBINATION WITH PERINDOPRIL// Therapeutic archive.- 2012. - No.12. - P. 30-35

26. Petelina T.I., Musikhina N.A., Gapon L.I., Dementjeva N.V. PROSPECTIVE ANALYSIS OF LIPID PROFILE PARAMETERS, INFLAMMATORY RESPONSE AND ENDOTHELIAL FUNCTION MARKERS BEFORE AND AFTER PERCUTANEUS CORONARY INTERVENTION IN PATIENTS WITH STABLE ANGINA // Kazan Medical Journal. - 2012- No.5.- P. 772-776.

27. Petelina T.I., Avdeeva K.S., Musikhina N.A., Gapon L.I. Abdominal obesity as a significant risk factor and predictor of the development of comorbid cardiometabolic disorders in patients with arterial hypertension // European Journal of Preventive Cardiology – Vol.26, Issue 1_suppl, June 2019. Abstract Book of EuroPrevent 2019, 11-13 April 2019, Lisbon, Portugal. S117. P592.

28. Petelina T.I., Musikhina N.A., Sharoyan U.A., Kostousova A.I. The role of the immuno-inflammatory parametory response in the development of repeated undesirable events in patients with unstable angina and type 2 diabetes mellitus. Results of prospective follow-up after angioplasty // European Heart Journal: Acute Cardiovascular Care - 8: 213-214, P486. Abstracts of the Acute Cardiovascular Care 2019, Malaga, Spain, 2-4 March 2019.

29. Petelina T.I., Musikhina N.A., Gapon L.I., Sharoyan Yu.A., Avdeeva K.S., Kostousova A.I., Zueva E.V., Leonovich S.V. The role of markers of the vascular inflammatory response in the diagnosis of recurrent adverse events in patients with unstable angina and type 2 diabetes mellitus after percutaneous coronary interventions // Clinica Chimica Acta - Vol.493, Suppl.1 (June 2019), s183. T195. Abstracts of EuromedLab 2019 - 23rd IFCC-EFLM European Congress of Clinical Chemistry and Laboratory Medicine, 19-23 May 2019, Barcelona, Catalonia. doi:10.1016/j.cca.2019.03.381.

30. Petelina T.I., Avdeeva K.S., Musikhina N.A., Gapon L.I., Zyryanova L.I., Leonovich S.V., Zueva E.V., Valeeva L.L., Polivtseva N.V. The contribution of biochemical parameters to the diagnosis of lesions of target organs in patients with arterial hypertension and abdominal obesity // Clinica Chimica Acta - Vol.493, Suppl.1 (June 2019), s171-s172. T171. Abstracts of EuromedLab 2019 - 23rd IFCC-EFLM European Congress of Clinical Chemistry and Laboratory Medicine, 19-23 May 2019, Barcelona, Catalonia. doi:10.1016/j.cca.2019.03.357.

31. Petelina T., Avdeeva K., Musikhina N., Gapon L., Zyryanova L., Bycova S., Zueva E. Association of vascular inflammatory response markers with parameters of vascular stiffness, signs of subclinical atherosclerosis, and bone mineral density in postmenopausal arterial hypertension // Atherosclerosis: «87th Congress of the European-Atherosclerosis-Society (EAS)», 26-29 May 2019, Maastricht, Netherlands. – 2019. - V.287. – р. E242. Poster EAS19-0140 https://elibrary.ru/item.asp?id=39381576.

32. Petelina T., Avdeeva K., Bycova S., Musikhina N., Gapon L., Zueva E. Nonspecific inflammatory response parameters in the pathogenesis of vascular wall and bone remodeling in postmenopausal female patients with arterial hypertension // Osteoporosis International: «World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO)», 04 - 07 April 2019 г., France, Paris. - 2019. - Volume 30, Supplement 2. - С. S293-S294. Poster P187. https://doi.org/10.1007/s00198-019-04989-6.

33. TI Petelina, NA Musikhina, LI Gapon, KS Avdeeva, SG Bycova, EV Zueva, NL Listsova. Postmenopausal female patients with arterial hypertension: non-specific inflammatory response parameters as a predictor of vascular wall stiffness, subclinical atherosclerosis and bone remodeling // Cardiovascular Innovations and Applications, Vol.4, Suppl.1, 2019. C106, GW30-e0411. Abstracts of the 30th Great Wall International Congress of Cardiology, Beijing, China, 10-13 October 2019. ISSN 2009-8618, e-ISSN 2009-8782.

34. Petelina T.I., Musikhina N.A., Gapon L.I., Sharoyan Y.A., Gorbatenko E.A. Features of Biochemical Parameters of Blood Serum in Patients with Stable Angina and Type 2 Diabetes Mellitus // Endocrinology & Metabolism International Journal - 2018. –Vol. 6, Issue 1 00147. DOI: 10/15406/emij.2018/06/00147.

35. Enina TN, Kuznetsov VA, Soldatova AM, Petelina TI, Krinochkin DV, Rychkov AY, Nochrina OY. Gender in cardiac resynchronisation therapy // Journal of Cardiovascular and Thoracic Research, 2018;10(4): 197-202. DOI: 10.15171/jcvtr.2018.34.

36. N. Musikhina, T. Petelina, N. Galeeva, A. Kostousova, L. Gapon. Lipid profile and biochemical markers of inflammation in patients with unstable angina and obstructive versus non-obstructive coronary artery disease // Atherosclerosis, Vol 275, e114, P1.1.036. Abstracts of the 86th European Atherosclerosis Society (EAS) Congress – 2018, May 05-08, Lisbon, Portugal. DOI: https://doi.ore/10.1016/i.atherosclerosis.2018.06.321

37. T. Petelina, N. Musikhina, L. Gapon, U. Sharoyan. The role of statins in prevention of acute coronary events in patients with coronary heart disease before and after coronary angioplasty and stenting // Atherosclerosis, Vol 275, e223, P5.2.414. Abstracts of the 86th European Atherosclerosis Society (EAS) Congress – 2018, May 05-08, Lisbon, Portugal. DOI: https://doi.ore/10.1016/i.atherosclerosis.2018.06.701.

38. Gapon L.I., Petelina T.I., Musikhina N.A., Avdeeva K.S., Leonovich C.V., Zhevagina I.A., Sagadieva S.D. Сhanges in the level of lipid and inflammatory parameters as pathogenetic basis of vascular remodeling in patients with arterial hypertension and metabolic disorders // Journal of Hypertension: Abstracts of the 28 European Meeting on Hypertension and Cardiovascular Protection, Barcelona, Spain, 8-11 June, 2018, Volume 36,e-Supplement 1, e96

39. Petelina T.I., Musikhina N.A., Avdeeva K.S., Gapon L.I., Dobrynina L.A., Kopylova L.N., Zhevagina I.A. Features of 24-hour blood pressure profile, vascular wall stiffness parameters and markers of vascular inflammatory reaction in postmenopausal female patients // Journal of Hypertension: Abstracts of the 28 European Meeting on Hypertension and Cardiovascular Protection, Barcelona, Spain, 8-11 June, 2018- Volume 36,e-Supplement 1, e40

40. Petelina T., Musikhina N., Gapon L. Avdeeva K., Bycova S., Dobrynina L. Postmenopausal female patients with arterial hypertension: inflammatory markers in the pathogenesis of subclinical atherosclerosis and osteoporosis. // Journal of Hypertension: Abstracts of the 28 European Meeting on Hypertension and Cardiovascular Protection, Barcelona, Spain, 8-11 June, 2018- Volume 36,e-Supplement 1, e206

41. TI Petelina, NA Musikhina, NA Galeeva, UA Sharoyan, AI Kostousova. Biochemical markers in the prognosis of the development of unstable angina in patients after coronary angioplasty and stenting // European Heart Journal - Acute Cardiovascular Care 2018: Volume: 7 issue: 1_suppl, page: 268 Article first published online: March 2, 2018; Issue published: March 1, 2018 https://doi.org/10.1177/2048872617751067

42. Avdeeva К.S., Petelina T.I., Gapon L.I., MusikhinaN.A., Kopylova L.N. Vascular wall stiffness parameters as risk factors of cerebrovascular complications in hypertensive patients with abdominal obesity // Cardiovascular Research: Frontiers in Cardiovascular Biology 2018, April 20-22, Vienna, Austria 114 (suppl_1): P 115