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Methods: The study included 739 male and 236 female patients (975) who underwent PCI. To determine level of
social support, the Multidimensional Scale of Perceived Social Support was used. The mean duration of a prospective
follow-up was 12.0 ± 1.7 months.
The Cox multivariate regression proportional hazard model was
used to estimate the hazard ratio (HR) of death from all causes and cardiovascular disease (CVD).
Results: A low level of social support in 5.7% of patients was observed, while 30.5% had a moderate level and
63.8% had a high level.
Patients with low and moderate levels of social support were older than those with high
level. Among patients with high levels of social support, more were male compared to patients with moderate
level.
During observation, 24 patients died from all causes (2.5%), while 21 (2.2%) died from CVD. In the
multivariate Cox regression model the HR of social support for all causes of death was 0.97 (95% confidence
interval, [CI], 0.94–0.99, p=0.007), while death from CVD was 0.97 (95% CI, 0.94–1.00, p=0.048).
For
patients with low level of social support, the HR for death from all causes was 4.52 (95% CI, 1.37–14.95,
p=0.013), while death from CVD was 3.66 (95% CI, 0.94–14.25, p=0.061).
Conclusion: Social support level was associated with age and gender, and significantly and independently affected
CAD patients' risk of death after PCI.
ЦЕЛИ: Предварительный анализ выявил степень, в которой алирокумаб уменьшал общие (первые и последующие) нефатальные сердечно-сосудистые события и смертность от всех причин в исходах ODYSSEY.
Цель: После острого коронарного синдрома диабет увеличивает риск развития ишемических сердечно-сосудистых событий.
BACKGROUND:After ACS, alirocumab added to intensive stain therapy favourably impacted on Type l and 2 MIs.
