Адреса и телефон
During the meeting, Elena Yaroslavskaya, MD, PhD, Head of Laboratory of instrumental diagnostics, Scientific Department of instrumental research methods, presented a report. The purpose of the study was to investigate the effect of COVID-19-associated pneumonia on structural and functional parameters of bronchopulmonary, cardiovascular systems, psychosocial status of patients during 12-month follow-up period to identify predictors of remodeling of studied organs and systems.
The study participants were 380 patients over 18 years old with laboratory-confirmed diagnosis of COVID-19-associated pneumonia three months after discharge.
Elena Ilyinichna presented the first results of the annual follow-up of patients after coronavirus: in long-term periods of disease, myocardial deformation was revealed. Difficulties in cardiac functioning were found in 28 % of patients 3 months after disease, in 58 % were registered in a year. Idea of deformity in the context of myocardium (heart muscle) differed from the common one. Elena Yaroslavskaya explained that it was normal to deform during each cardiac cycle for a healthy heart. Conversely, when parameters of myocardial deformation were reduced, this might be early manifestation of disordered cardiac contractility. In connection with the importance of structural and functional remodeling of myocardium, revealed in the long term, our study would be continued. The scientist shared her research would be aimed to create a model for predicting an unfavorable course of long-term period in various groups of patients.
It was already clear that heart problems could occur not only in elderly patients: mean age of already examined was only 49 years old, men and women in equal proportion. Someone had disorder in cardiovascular system functioning for the first time; someone had previously existing diseases deterioration. Moreover, she said, “victims” of covid-19 had been increasing over time. Depending on affected strain, post-covid course certainly changed; scientists had yet to analyze those, as research continued. Elena Ilyinichna also explained that, according to the assessment of myocardial deformation disorders, physicians were able to find out a group of patients whose recovery period would be proceed unfavorably. These patients would need more attention as they were at risk of developing diseases such as heart failure or arrhythmias. But the timing and scenarios of disease development might be different, depending on pre-existent health status. Elena Ilyinichna Yaroslavskaya assured scientists would be able to answer that question after finishing the analysis of results.
There had been no vaccinated persons among 380 patients, but now we were recruiting a control group from vaccinated people who had not had clinical manifestations of the disease. Changes of mental health were very indicative. About 60 percent of our patients showed violations of anxiety spectrum: the most common symptoms were severe asthenia, causeless anxiety, sleep disturbances.
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Vadim Stepanov, Director of Tomsk NRMC, Corresponding Member of RAS, Professor, considered Tyumen Cardiology Research Center - Branch of Tomsk NRMC, as one of the current leaders in the aspect of post-covid syndrome study in the long-term follow-up. New data obtained on the assessment of myocardial deformation characteristics did not only fix the problem, but also did the groundwork for the development of approaches to the treatment and rehabilitation of patients who underwent COVID-19 and post-covid syndrome.
